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Year 2012 - Volume 32, Number 11
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Susceptibility to disinfectants and antimicrobial resistance profile in Escherichia coli isolates, 32(11):1116-1120
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ABSTRACT.- Krewer Ca.C., Gressler L.T., Costa M.M., Krewer Cr.C. & Vargas A.C. 2012. [Susceptibility to disinfectants and antimicrobial resistance profile in Escherichia coli isolates.] Suscetibilidade a desinfetantes e perfil de resistência a antimicrobianos em isolados de Escherichia coli. Pesquisa Veterinária Brasileira 32(11):1116-1120. Laboratório de Microbiologia e Imunologia Animal, Universidade Federal do Vale do São Francisco, Rodov. BR 407 Km 12, Lote 543, Projeto de Irrigação Nilo Coelho s/n C1, Petrolina, PE 56300-000, Brazil. E-mail: mateus.costa@univasf.edu.br
Colibacillosis caused by Escherichia coli is the most important enteric disease in pig production, which may lead to death of the affected animal. The bacterium has a great ability to develop resistance to multiple antibiotics and disinfectants. Thus, investigation addressing mechanisms of resistance and profile of field samples is necessary. E. coli is widely used as a model for studies that explore the intrinsic and extrinsic resistance to multidrugs. In this paper, we attempt to associate the susceptibility profile of 62 isolates of E. coli to three disinfectants and 13 antimicrobials. Also 31 isolates were tested for the presence of efflux mechanism. Of the three disinfectants tested, alkyldimethylbenzylammonium chloride+nonyl phenoxy polyethoxy ethanol was the most effective (100%), followed by glutaraldehyde+alkyldimethylbenzylammonium chloride (95.2%) and alkyldimethylbenzylammonium chloride (88.8%). Among the antimicrobials tested, there was greater resistance to tetracycline (62.2%) and higher sensitivity to florfenicol (88.6%). The high sensitivity of the isolates against disinfectants may be related to the absence of efflux mechanism. The average index of multiple resistance to antimicrobials was 0.52, what demonstrates a profile of multidrug resistant isolates, showing the need for rational use of these drugs in pig production. |
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