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Year 2001 - Volume 21, Number 1
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Histological changes caused by experimental Riedeliella graciliflora (Leg. Papilionoideae) poisoning in cattle and laboratory animals, 21 (1):5-7
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ABSTRACT.- Riet-Correa F., Górniak S.L., Haraguchi M. & Dagli M.L.Z. 2001. Histological changes caused by experimental Riedeliella gracili.flora (Leg. Papilionoideae) poisoning in cattle and laboratory animals. Pesquisa Veterinária Brasileira 21 (1):5-7. [Alterações histológicas na intoxicação experimental por Riedeliella graciliflora (Leg. Papilionoideae) em bovinos e animais de laboratório.] Laboratório Regional de Diagnóstico, Faculdade de Veterinária, Universidade Federal de Pelotas, 96010-900 Pelotas, RS, Brazil.
Tissues from cattle, mice, rats and guinea pigs experimentally intoxicated by Riedeliella graciliflora were studied histologically. Cattle lymph nodes, spleen, Peyer patches and peribronchial lymphoid tissues had diffuse necrosis of lymphocytes, mainly in the germinal centers of the follicles. This lesion was less severe in laboratory animals. All species had severe enteritis with infiltration of the lamina propria by mononuclear cells. Some cells in this infiltrate were necrotic. Degeneration and necrosis of the epithelial cells, mainly in the tip of the villi, and detachment of the epithelial lining from the lamina propria were also observed. In the liver the trabecular structure was disrupted and the hepatocytes had some degree of individual necrosis and degeneration. A tubular nephrosis was observed in the kidneys. Liver, lung, kidney, intestine and lymph nodes had different degrees of congestion. Those lesions are similar than those caused by Polygala klotzscllii, a plant that contains 5-metoxi-podophyllotoxin. |
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