Resultado da pesquisa (2)

Termo utilizado na pesquisa starvation

#1 - Starvation and refeeding in rats: effect on some parameters of energy metabolism and electrolytes and changes of hepatic tissue, 36(Supl.1):101-105

Abstract in English:

ABSTRACT.- Namazi F., Omidi A., Abbasi S., Afsar M., Honarmand M. & Nazifi S. 2016. Starvation and refeeding in rats: effect on some parameters of energy metabolism and electrolytes and changes of hepatic tissue. Pesquisa Veterinária Brasileira 36(Supl.1):101-105. Department of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran. E-mail: fnamazi@shirazu.ac.ir Regarding the importance of starvation and refeeding and the occurrence of refeeding syndrome in various conditions, the present study was conducted to investigate the effects of refeeding on some parameters of energy metabolism and electrolytes and changes of hepatic tissue in male Wistar rats. Fifty-seven rats were divided into six groups, having 6 to 11 rats. Food was provided ad-libitum until three months and then the first group was considered without starvation (day 0). Other rats were fasted for two weeks. Group 2 was applied to a group immediately after starvation (day 14). Groups 3 to 6 were refed in days 16 till 22, respectively. At the end of each period, blood and tissue samples were taken and histopathological and serum analysis, including serum electrolytes (calcium, phosphorus, sodium, potassium), the energy parameters (glucose, insulin, cortisol) and the liver enzymes (ALT, AST, ALP) were determined. Insulin decreased by starvation and then showed an increasing trend compared to starvation period, which the highest amount of this parameter was observed eight days post-refeeding. Serum glucose level showed the opposite pattern of insulin. Histopathological examination of the tissue sections revealed clear vacuoles after starvation and refeeding, in which the severity of lesions gradually decreased during refeeding. The cortisol level decreased by starvation and then increased during refeeding. Also, potassium and phosphorus concentrations declined by refeeding and the serum sodium and potassium levels were changed in the relatively opposite manner. The calcium level decreased by starvation and then increased during refeeding. These results could help recognize and remedy the refeeding syndrome.

Abstract in Portuguese:

ABSTRACT.- Namazi F., Omidi A., Abbasi S., Afsar M., Honarmand M. & Nazifi S. 2016. Starvation and refeeding in rats: effect on some parameters of energy metabolism and electrolytes and changes of hepatic tissue. Pesquisa Veterinária Brasileira 36(Supl.1):101-105. Department of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran. E-mail: fnamazi@shirazu.ac.ir Regarding the importance of starvation and refeeding and the occurrence of refeeding syndrome in various conditions, the present study was conducted to investigate the effects of refeeding on some parameters of energy metabolism and electrolytes and changes of hepatic tissue in male Wistar rats. Fifty-seven rats were divided into six groups, having 6 to 11 rats. Food was provided ad-libitum until three months and then the first group was considered without starvation (day 0). Other rats were fasted for two weeks. Group 2 was applied to a group immediately after starvation (day 14). Groups 3 to 6 were refed in days 16 till 22, respectively. At the end of each period, blood and tissue samples were taken and histopathological and serum analysis, including serum electrolytes (calcium, phosphorus, sodium, potassium), the energy parameters (glucose, insulin, cortisol) and the liver enzymes (ALT, AST, ALP) were determined. Insulin decreased by starvation and then showed an increasing trend compared to starvation period, which the highest amount of this parameter was observed eight days post-refeeding. Serum glucose level showed the opposite pattern of insulin. Histopathological examination of the tissue sections revealed clear vacuoles after starvation and refeeding, in which the severity of lesions gradually decreased during refeeding. The cortisol level decreased by starvation and then increased during refeeding. Also, potassium and phosphorus concentrations declined by refeeding and the serum sodium and potassium levels were changed in the relatively opposite manner. The calcium level decreased by starvation and then increased during refeeding. These results could help recognize and remedy the refeeding syndrome.


#2 - Perinatal lamb mortality in three counties in Rio Grande do Sul

Abstract in English:

A study on ovine perinatal mortality was done on one farm near Bagé in 1978 and on 15 farms in the counties of Bagé, Pelotas and Santa Vitória do Palmar, Rio Grande do Sul, in 1979. Six hundred and twelve lambs were necropsied. The most commom cause of death was starvation/exposure which accounted for 58.2% of deaths in 1978 and 56.7% in 1979. Dystocia was the second cause of mortality, 8.6% in 1978 and 22.9% in 1979. Predators were the primary cause of death of 2.4% of necropsied lambs, in 1979. Other causes of death (congenital infections, neonatal infections, congenital malformations) were not considered important in the total number of mortalities. When a comparison was made of birth weights on one farm, it was observed that those lambs that died had weighed significantly less than those that survived (P < 0.01). Lambs which had died from starvation/exposure were significantly lighter than those that died of complications due to dystocia (P < 0.01). Lambing percentages, lamb mortality and survival rate were determined on seven of the farms studied in 1979. Perinatal mortality (21%) was the main cause of the low reproductive performance on only one farm. Although lamb mortality was not great, between· 8 and 13% on the rest of the farms, the low marking percentage, between 66 and 84%, was due to low lambing rates.

Abstract in Portuguese:

O estudo foi realizado em um estabelecimento de Bagé em 1978, e em 15 estabelecimentos de Bagé, Pelotas e Santa Vitória do Palmar, RS, em 1979. Pela necropsia de 612 cordeiros, observou-se que a causa mais freqüente de mortalidade foi o complexo inanição/exposição (58,2% em 1978 e 56,7% em 1979), ficando a distocia em segundo lugar (8,6% em 1978 e 22,9% em 1979). A predação primária foi diagnosticada em 2,4% dos cordeiros necropsiados, não sendo causa importante de mortalidade, já que foi superada tanto pela predação secundária como pela de pós-morte. Infecções congênitas, infecções neonatais e malformações congênitas também não foram causas importantes no total das mortes. Em um estabelecimento os cordeiros foram pesados ao nascimento e verificou-se que os que morreram foram significativamente mais leves que os sobreviventes (P < 0,01). Os cordeiros mortos devido ao complexo inanição/exposição foram significativamente mais leves (P < 0,01) do que os mortos por distocia. Em 7 dos estabelecimentos estudados em 1979, foram determinadas as porcentagens de parição, de mortalidade de cordeiros e de assinalação. Somente em um estabelecimento a mortalidade perinatal (21%) foi a principal causa de baixa eficiência reprodutiva. Nos 6 restantes, apesar de a mortalidade ter sido considerada baixa (entre 8 e 13%), a porcentagem de assinalação variou entre 66 e 84%, devido, aparentemente, às baixas taxas de parição.


Colégio Brasileiro de Patologia Animal SciELO Brasil CAPES CNPQ UNB UFRRJ CFMV